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We’ve been successful to take models like snails, like yeast, like nematodes, like flies, like rats, like monkeys and to extend their healthy life span with either genetic manipulations or manipulations with the environment or with drugs, so we have proven the pre-concept here, again and again.
Found on FOX News 8 years ago
We kind of know what are the main nodes that have to happen for the body to be resilient to stresses and be able to live longer. They include pathways like the insulin signaling pathway or the growth pathway and some other mechanisms, it happens that this drug, metformin, works on several of those mechanisms that are so crucial to stop the aging process— glucose being one of them but not a central one.
Found on FOX News 8 years ago
We have a lot of data that shows it can work, but we have to do the study the way the FDA wants us to do the study, so we are working on the protocol and continue to talk to the FDA to get them to approve the specifics of what we want to do.
Found on FOX News 8 years ago
What we do find that they have is genes that are protecting them against anything that’s thrown their way— those are individual cells that have mutations that we think are associated with longevity.
Found on FOX News 8 years ago
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