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Dr. Isobel "Izzie" Stevens: I believe in the good. I believe that it's been a hell of a year. And I believe, in the face of overwhelming evidence to the contrary, we will all be okay. I believe a lot of things. I believe that Denny is always with me. And I believe that if I eat a tub of butter, and no one sees me, the calories don't count. And I believe that surgeons who prefer staples over stitches are just lazy. [Turns to George] I believe you are a man who made a terrible mistake by marrying Callie. And I believe that because you're my best friend, I can tell you this and we can be okay. I believe even though you made this mistake, you will be okay, I believe we survive, George. I believe that believing we survive is what makes us survive.

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